Details for Lipidomes in health and disease: Analytical strategies and considerations

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Name:Lipidomes in health and disease: Analytical strategies and considerations
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Lipidomics is a rapidly-growing field which focuses on global characterization of lipids at molecular and systems levels. As small changes in the concentrations of lipids may have important physiological consequences, much attention in the field has recently been paid to more accurate quantitation and identification of lipids. Community-wide efforts have been initiated, aiming to develop best practices for lipidomic analyses and reporting of lipidomic data. Nevertheless, current approaches for comprehensive analysis of lipidomes have some inherent challenges and limitations. Additionally, there is, currently, limited knowledge concerning the impacts of various external and internal exposures on lipid levels. In this review, we discuss the recent progress in lipidomics analysis, with a primary focus on analytical approaches, as well as on the different sources of variation in quantifying lipid levels, both technical and biological.

Authors:Wei, F. et al
Journal Title:Trends in Analytical Chemistry
Journal Year:2019
Volume / Issue No.:120
Digital Object Identifier:http://dx.doi.org/10.1016/j.trac.2019.115664
Filename:Wei_TrAC_2019.pdf
Filesize: 1.22 MB
Filetype:pdf (Mime Type: application/pdf)
Creator:ixscient
Created On: 12/23/2019 11:03
Viewers:Everybody
Maintained by:ixscient
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Last updated on: 12/23/2019 11:05
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